The NFL season officially kicked off last night with the Colts playing the Saints. That means the fantasy football season is finally underway. Here are some things to watch for in the weekend games.

Match-up benefits:

— Anquan Boldin. San Francisco’s new addition Nate Clements provides a sufficient challenge to Arizona wide receiver Larry Fitzgerald. However, the 49ers do not have much depth at cornerback behind Clements. This should allow Boldin to have a big game since he is a more potent option going against San Francisco’s No. 2 cornerback.

— Dallas Offense. Pick any player you want and they will have the advantage over an aging and less-than-impressive Giants defense. Even though I would never own him on my team, Terrell Owens could have a huge game Sunday. Even Tony Romo could look better than Eli Manning this weekend.

— San Diego Defense. How could they not have the edge? They are playing a team led by Rex Grossman. Chicago is also debuting first-year starter Cedric Benson at running back Sunday. That’s enough to sell me on the Chargers defense. Add a shaky receiving corps and I can almost guarantee a shutout.

Match-up problems:

— Lee Evans. Lee Evans could have a stellar year, but he has to start off against the best cornerback in the NFL. Champ Bailey is arguably the only cover corner left in the league. He gives every wide receiver problems and Lee Evans will be no different. It was no mistake that Bailey led the league in interceptions last year.

— Green Bay rushing offense. Whoever ends up being the starting running back will face trouble this weekend against the Eagles, whether it’s Vernand Morency or Brandon Jackson. The Eagles return most of the parts of a defense that was ranked 7th overall last season according to Espn.com. The Packers will have a tough time on offense, especially running the ball.

— Tavaris Jackson. It will be a tough day for the Vikings first-year starter. He is a mobile quarterback, but he faces an Atlanta defense that was ranked third last year in rushing defense according to Espn.com. Bill Simons justified Adrian Peterson as one of his top 50 fantasy players by saying, “Yeah, he’s splitting time with Chester Taylor and probably rushing against the first 11-0-0 defensive formation because of Tavaris Jackson, but you never know.” That statement alone should haunt Jackson as he heads into his first career start on Sunday.

— Chiefs Secondary. This may be a pattern throughout the season. The Chiefs pass defense is almost always at the bottom of the league rankings, and that spells trouble this year when they barely have an offense. It’s even more trouble when they are mismatched in their first game against the Houston Texans. The Texans added quarterback Matt Schaub and have a solid receiver in Andre Johnson that will create major problems for the Chiefs secondary. Jacoby Jones may even cause problems for the Chiefs.

Game to watch:

— San Francisco vs. Arizona. San Francisco made a lot of smart moves in the off-season and has built up a solid team that will compete at a high level in the NFC West this year. Arizona has taken gradual steps toward success the past few years. Do not be surprised if this year’s NFC West is similar to the NL West in baseball, consisting of a lot of teams with very close records. Monday Night will be all about the offenses, and if you have any of those players on your team, look for a lot of points to roll your way, unless, of course, you have the Cardinals or 49ers defenses.

— Edited by Kyle Carter