What do you know about: CARS

Wednesday, January 25, 2012

Rongqing Hui, professor of electrical engineering and computer science.

In many senses, the technological growth of a nation is now measured by how much it can shrink its phones, computers, mp3 players and the like. Keeping up with Moore’s Law, to double the processing power and cut prices by half, is a pursuit that has forged the epicenters of modern technology. Meanwhile, one of the most advanced applications of this pursuit has been taking place right here in Lawrence. Carey Johnson, a KU professor of Chemistry, and Rongqing Hui, a KU professor of electrical engineering and computer science, have been steadily closing in on a method of making the cutting edge of laser imaging available to society as a whole. According to Johnson, Coherent anti-Stokes Raman Spectroscopy (CARS) is a method of laser imaging used in biomedical science to directly observe DNA and the other building blocks of life.

CARS works through triangulating the unique resonant frequencies of elements by emitting variable wavelengths of light, a method that both preserves the sample and eliminates unnecessary steps.

Carey Johnson, professor of Chemistry

”CARS has been around for a long time, but it’s been developed based on $300,000 laser systems that take up large optical tables,” Johnson says. “It’s not a very usable method of microscopy for everyday clinical use — it requires a very specialized lab and a system that’s not portable.”

By making use of a $156,000 grant from the National Institutes of Health, Johnson and Hui stand a chance to revolutionize biomedicine and clinical work by re-engineering CARS to fit inside a shoebox. The project, scheduled for completion by 2014, could mainstream methods of DNA analysis and testing previously available only to the wealthiest and most prestigious institutions.

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